Paul is dedicated toward a career as an academic cardiac surgeon with a focus on developing novel therapeutic approaches to treat patients with congestive heart failure. His Ph.D. thesis outlines an important role for TIMP-3 as a key regulator of the remodeling process in the failing heart and he is now focused on translating these novel findings into experimental gene and cell therapies for patients with heart failure. His other research interests include the pathophysiology and treatment of bicuspid aortic valve disease, endothelial dysfunction during allograft preservation for transplantation, and the mechanisms underlying the benefits of cell transplantation for cardiac dysfunction.
