Dr. Ramzy has a clinical interest in the surgical treatment of end-stage heart disease and cardiac allograft vasculopathy. Danny's career goal is to become a cardiac surgeon-scientist who can serve patients in a clinical setting while bringing research from the bench to the bedside. His research currently investigates novel techniques of myocardial and endothelial protection for cardiac transplantation and new therapeutic strategies to prevent cardiac allograft vasculopathy. Prevention of cardiac allograft vasculopathy would have great clinical benefit as it is the principal late cause of death following cardiac transplantation. Danny's Ph.D. focuses on the mechanisms behind endothelin-1 induced cardiac allograft vasculopathy. More specifically his work outlines the role of protein kinase C in endothelin-1 induced impairment of nitric oxide homeostasis in vascular endothelial cell.
Left to Right: Danny Ramzy and Pixie Bigelow